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FACTORS AFFECTING PLASMA ANGIOTENSIN II CONCENTRATION IN LABOUR
Author(s) -
Symonds E. M.,
Pipkin Fiona Broughton
Publication year - 1980
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1980.tb04439.x
Subject(s) - caesarean section , vaginal delivery , medicine , elective cesarean section , elective caesarean section , angiotensin ii , blood pressure , pregnancy , caesarean delivery , obstetrics , endocrinology , biology , genetics
Summary Concentrations of plasma angiotensin II (All) have been measured in the second stage of labour or before delivery by elective Caesarean section in 134 women and some factors influencing the levels have been assessed. Plasma All concentrations in the second stage of labour were higher than levels previously observed before the onset of labour in both primigravid and multiparous women. Markedly lower levels were found following delivery by elective Caesarean section than following vaginal delivery. Multiparae had higher All concentrations than primigravidae both before the onset of labour and at delivery. Epidural analgesia was associated with significantly lower All concentrations; in primigravidae receiving such analgesia a statistically significant relation was found between All concentration and diastolic blood pressure at delivery. A similar relation was found in the non‐proteinuric patients delivered by Caesarean section. The estimated duration of the second stage of labour was the major factor affecting All concentration in normal multiparae. In both primigravid and multiparous women, All concentrations were markedly raised in association with proteinuria.