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SEQUENTIAL CHANGES IN THE HUMAN RENIN‐ANGIOTENSIN SYSTEM FOLLOWING THERAPEUTIC TERMINATION OF PREGNANCY
Author(s) -
Broughton Pipkin F.,
Oats J. J. N.,
Hunter J. C.,
Craven D. J.,
Symonds E. M.
Publication year - 1979
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1979.tb11257.x
Subject(s) - renin–angiotensin system , plasma renin activity , medicine , pregnancy , blood pressure , angiotensin ii , endocrinology , therapeutic abortion , cannula , gestational age , anesthesia , abortion , surgery , biology , genetics
Summary Plasma renin and angiotensin II levels were measured in nine patients immediately before and at half‐hourly intervals in the four hours following therapeutic termination of pregnancy. There was a small fall in renin and angiotensin II levels over the first 1 to 2 hours, followed by a slight increase. The magnitude of these effects was much smaller than those previously seen following normal delivery. It is concluded that in early pregnancy maternal, rather than feto‐placental, factors are controlling the renin‐angiotensin system.