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INDOMETHACIN IN THE TREATMENT OF PRIMARY DYSMENORRHOEA
Author(s) -
Elder M. G.,
Kapadia L.
Publication year - 1979
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1979.tb10828.x
Subject(s) - medicine , vomiting , placebo , pain relief , nausea , anesthesia , double blind , prostaglandin , surgery , alternative medicine , pathology
Summary Thirty‐two patients were treated with placebo tablets or indomethacin (25 mg three times daily) in a six‐month, double‐blind, cross‐over trial. During indomethacin therapy, 75 per cent of patients experienced significant pain relief while associated vomiting and diarrhoea were relieved in 44 per cent and 64 per cent of patients respectively. The efficacy of indomethacin was comparable to that of other prostaglandin synthetase inhibitors.