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THE COMPOSITION OF AMNIOTIC FLUID IN PREGNANCIES COMPLICATED BY FETAL ANENCEPHALY OR SPINA BIFIDA
Author(s) -
Pettit B. R.,
Baker S. P.,
King G. S.
Publication year - 1979
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1979.tb10826.x
Subject(s) - anencephaly , spina bifida , amniotic fluid , fetus , potassium , medicine , obstetrics , pregnancy , sodium , chemistry , biology , surgery , genetics , organic chemistry
Summary The concentration of amniotic fluid glucose, total protein, sodium, potassium, calcium, magnesium and phosphate as well as amniotic fluid osmolality were measured in normal second trimester pregnancies and in second trimester pregnancies complicated by fetal anencephaly or spina bifida. Amniotic fluid glucose concentration was low in anencephaly, while phosphate and total protein were high; calcium concentration and osmolality were slightly elevated with spina bifida. The application of these findings to antenatal diagnosis are discussed.