Premium
ENTAL INTERVILLOUS BLOOD FLOW MEASURED BY INHALED 133 Xe CLEARANCE IN RELATION TO INDUCTION OF EPIDURAL ANALGESIA.
Author(s) -
Husemeyer R.P.,
Crawley J.C.W.
Publication year - 1979
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1979.tb10784.x
Subject(s) - anesthesia , bupivacaine , blood pressure , medicine , blood flow , hemodynamics , nuclear medicine , cardiology
Summary A method of determining placental intervillous blood flow (IBF) using an inhaled 133 Xe technique is described. The method was used to investigate the effect on IBF of epidural analgesia with an initial dose of 37.5 mg bupivacaine. There was no statistically significant reduction in IBF following the initial dose of bupivacaine in spite of a small but statistically significant reduction in mean blood pressure. There was no significant correlation between the change in mean blood pressure and the percentage change in IBF following epidural block although the single largest percentage reduction in IBF was associated with the largest fall in mean blood pressure.