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THE RECURRENCE RATE AND SIGNIFICANCE OF LOW OESTRIOL EXCRETION IN SUCCESSIVE PREGNANCIES
Author(s) -
Oats J. J. N.,
Beischer N. A.
Publication year - 1979
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1979.tb10676.x
Subject(s) - excretion , medicine , pregnancy , incidence (geometry) , obstetrics , estriol , fetus , population , physiology , gynecology , endocrinology , biology , estrogen , mathematics , genetics , environmental health , geometry
Summary A total of 440 women who had low oestriol excretion in a previous pregnancy was investigated by urinary oestriol assays in one or more subsequent pregnancies. The incidence of low oestriol excretion in the subsequent pregnancy was 29.1 per cent, or more than double that in the total obstetric population (13.4 per cent; p <0.001). Patients with persistently low oestriol excretion had a 40.8 per cent recurrence rate in subsequent pregnancies. When oestriol excretion was low in successive pregnancies it retained a significant association with increased incidences of stillbirths, neonatal deaths and fetal growth retardation. It was concluded that low oestriol excretion in a previous pregnancy is a definite indication to test fetoplacental function in subsequent pregnancies even when the clinical findings are normal.