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WATER RELATIONS OF THE OVARIAN CYCLE
Author(s) -
Good W.
Publication year - 1978
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1978.tb15827.x
Subject(s) - ovulation , follicular fluid , medicine , follicular phase , endocrinology , menstrual cycle , menstruation , ovary , biology , chemistry , hormone , microbiology and biotechnology , oocyte , embryo
Summary This study reports the likely pattern of change in serum osmolality during the normal ovarian cycle, together with that which occurs during ovulation‐induction by gonadotrophin. The variation in serum osmolality is attributed to the action of oestrogen on venous distensibility, and the effect of that response on the osmotic equilibrium between intra‐ and extravascular fluid. Although the action of gonadotrophin is mediated by the products of follicular theca and granulosa cells, the physiological response is ultimately affected by water. Both ovulation and menstruation may therefore depend on achieving a critical water content of follicular fluid and endometrial tissue.