Premium
CYCLIC CHANGES IN THE CONCENTRATION OF PROSTAGLANDIN F 2α IN HUMAN UTERINE FLUSHINGS
Author(s) -
Maathuis J. B.
Publication year - 1978
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1978.tb10483.x
Subject(s) - prostaglandin f2alpha , luteolysis , radioimmunoassay , luteal phase , menstrual cycle , medicine , uterus , endocrinology , menstruation , corpus luteum , chemistry , prostaglandin , follicular phase , hormone
Summary Prostaglandin F 2α (PGF 2α ) was measured by radioimmunoassay in uterine flushings obtained from 41 women at various stages of the menstrual cycle. The concentration of PGF 2α changed significantly during the cycle, with highest values in the mid secretory phase of the cycle (mean 9.1 ng/ml of uterine flushing, range 3.9 to 16.0 ng/ml, n = 9). The still unresolved role of intrauterine PGF 2α is discussed in relation to luteolysis, myometrial contractility and implantation.