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INDUCTION OF LABOUR BY PHARMACOLOGICAL AND PHYSIOLOGICAL DOSES OF INTRAVENOUS OXYTOCIN
Author(s) -
Toaff M. E.,
Hezroni J.,
Toaff R.
Publication year - 1978
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1978.tb10461.x
Subject(s) - oxytocin , medicine , incidence (geometry) , uterotonic , uterine contraction , tetany , anesthesia , uterus , obstetrics , mathematics , geometry
Summary In addition to membrane rupture, pharmacological doses of oxytocin (2·6 mU/ minute rising stepwise to 422·4 mU/minute) were used in 134 patients and the results compared to those obtained in 144 patients given only physiological doses of oxytocin (2·6 to 13·2 mU/minute). Pharmacological doses of oxytocin gave better results in terms of induction‐delivery intervals, incidence of failed inductions and puerperal morbidity. The incidence of hypertonus was similar in both groups and unrelated to oxytocin doses. A uterine activity of 276 Montevideo units, modified to 200 to 220 Montevideo units for grande multiparae, is defined as the goal of oxytocin treatment in induction of labour. A sign of imminent uterine tetany in the intrauterine pressure curve (the ‘damping sign’) is described.