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THE EFFECT OF INTRAUTERINE FETAL TRANSFUSION AND A β‐SYMPATHOMIMETIC SUBSTANCE ON THE LECITHIN/ SPHINGOMYELIN RATIO IN HUMAN AMNIOT1C FLUID
Author(s) -
Iddekinge B.,
Hughes Elizabeth A.
Publication year - 1977
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1977.tb12678.x
Subject(s) - amniotic fluid , medicine , lecithin , respiratory distress , anesthesia , incidence (geometry) , obstetrics , fetus , pregnancy , chemistry , biology , chromatography , genetics , physics , optics
Summary The apparently low incidence of respiratory distress syndrome in babies born prematurely after irstrauterine transfusion and the simultaneous prophylactic administration of intravenous isoxsuprine (a β‐sympathomimetic agent) was investigated by serial study of amniotic fluid lecithin/sphingomyelin ratios. The ratio rose very significantly after intrauterine transfusions and significantly (but less markedly) after the administration of intravenous isoxsuprine alone.