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PLASMA LEVELS OF PREGNANCY‐SPECIFIC β 1 ‐GLYCOPROTEIN IN COMPLICATED PREGNANCIES
Author(s) -
Towler C. M.,
Horne C. H. W.,
Jandial V.,
Campbell Doris M.,
MacGillivray I.
Publication year - 1977
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1977.tb12573.x
Subject(s) - placental lactogen , human placental lactogen , fetus , fetal growth , pregnancy , growth retardation , glycoprotein , endocrinology , medicine , andrology , obstetrics , chemistry , placenta , biology , biochemistry , genetics
Summary Maternal plasma levels of the trophoblast product, pregnancy‐specific β 1 ‐glycoprotein (PSβG), have been measured both in normal pregnancies and in pregnancies complicated by pre‐eclampsia and/or fetal growth retardation. PSβG levels correlate significantly with placental and fetal weight and fall below the normal range in about 60 per cent of all patients with fetal growth retardation. PSβG measurements appear to give a considerably better indication of fetal size than measurements of either human placental lactogen (HPL) or plasma oestriol.