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THE EFFECT OF ALTERING THYROID HORMONE CONCENTRATIONS ON PLASMA GONADOTROPHINS IN POSTMENOPAUSAL WOMEN
Author(s) -
Taylor M. A. R.,
Chapman C.,
Hayter C. J.
Publication year - 1977
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1977.tb12572.x
Subject(s) - endocrinology , medicine , luteinizing hormone , follicle stimulating hormone , carbimazole , hormone , thyroid , thyroid stimulating hormone , graves' disease
Summary Plasma gonadotrophin levels were measured at frequent intervals in six post‐menopausal thyrotoxic women treated with carbimazole. All patients showed an increasing follicle stimulating hormone/luteinizing hormone (FSH/LH) ratio as the thyroid hormone concentrations fell to normal and then into the hypothyroid range. Although the increased FSH/LH ratio was primarily due to a rise of FSH, two patients had a rise of both gonadotrophins. It is suggested that menstrual irregularities occurring in premenopausal women with disorders of thyroid metabolism may be related to similar changes.