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SIMULTANEOUS IN SITU CARCINOMA OF THE CERVIX, VULVA AND PERINEUM AFTER IMMUNOSUPPRESSIVE THERAPY FOR RENAL TRANSPLANTATION
Author(s) -
Leckie G. B.,
Cotton R. E.
Publication year - 1977
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1977.tb12543.x
Subject(s) - vulva , perineum , cervix , medicine , transplantation , urology , cervix carcinoma , surgery , cervical carcinoma , cancer , cervical cancer
Summary A 31‐year‐old woman developed multiple synchronous in situ carcinomas of the cervix uteri, vulva and perineal skin, six years after successful renal transplantation for chronic renal failure due to chronic pyelonephritis. During this time she had been continuously treated with immunosuppressive drugs (azathioprine and prednisolone). The lesions were treated by local excision and there was no evidence of recurrence nearly two years after the primary treatment. The case history is compared to others recently described and highlights the risk of epithelial as well as lymphomatous malignancies in renal transplant recipients.