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TREATMENT OF THE PREMENSTRUAL SYNDROME
Author(s) -
Robinson Kathleen,
Huntington Kathleen M.,
Wallace M. G.
Publication year - 1977
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1977.tb12493.x
Subject(s) - lethargy , irritability , medicine , placebo , randomized controlled trial , anesthesia , anxiety , psychiatry , alternative medicine , pathology
Summary A placebo‐controlled, randomized, double‐blind, parallel group study in hospital and general practice has shown that a combination of belladonna alkaloids, ergotamine tartrate, and phenobarbitone (Bellergal) was effective in treating troublesome symptoms of the premenstrual syndrome of which fatigue, tender breasts, nervousness, irritability, lethargy and listlessness were improved to a statistically significant degree. The drug was given three times daily and caused no side effects.