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THE EFFECT OF DOXAPRAM ON FETAL BREATHING IN THE SHEEP
Author(s) -
Hogg M. I. J.,
Golding R. H.,
Rosen M.
Publication year - 1977
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1977.tb12466.x
Subject(s) - doxapram , fetus , breathing , anesthesia , medicine , respiratory system , gestation , pregnancy , biology , genetics
Summary In five ewes of 105 to 120 days gestation intravenous doxapram (1·8 to 3·85 mg/kg) administered to the mother produced a dose‐related increase in fetal breathing. This effect of doxapram might prove useful as a test of human fetal health. Fetal breathing movements could be a sensitive indication of the effects of drugs on the human fetal respiratory system.