Premium
MEASUREMENT OF INTERVILLOUS AND MYOMETRIAL BLOOD FLOW BY AN INTRAVENOUS 133 Xe METHOD
Author(s) -
Rekonen A.,
Luotola H.,
Pltkänen M.,
Kuikka J.,
Pyörälä T.
Publication year - 1976
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1976.tb00921.x
Subject(s) - blood flow , intervillous space , bolus (digestion) , nuclear medicine , placenta , saline , intravenous bolus , medicine , anesthesia , anatomy , pregnancy , cardiology , fetus , biology , genetics
Summary A new ‘non‐invasive’ method for measuring intervillous and myometrial blood flow is presented. After 2 mCi of 133 Xe in physiological saline was injected intravenously the patient held her breath for 20 seconds. The tracer entered the placenta as a short bolus and its removal was followed with a scintillation detector. Intervillous and myometrial blood flow per unit volume was calculated from the two‐exponential curve. The mean ±SD intervillous flow in normal pregnancy was 135±49 ml/minute/100 ml, the corresponding half time being 0·56±0·16 minutes. The myometrial flow was 7 ·7±2·5 ml/minute/100 g. The method gave reproducible results and took only 20 minutes to perform. The dose of radiation to the mother was less than 1 mrad.