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THE EFFECT OF LABOUR ON ACTH AND CORTISOL LEVELS IN AMNIOTIC FLUID AND MATERNAL BLOOD
Author(s) -
Tuimala R.,
Kauppila A.,
Rönnberg L.,
Jouppila R.,
Haapalahti J.
Publication year - 1976
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1976.tb00917.x
Subject(s) - amniotic fluid , medicine , endocrinology , adrenocorticotropic hormone , hydrocortisone , adrenocorticotrophic hormone , pregnancy , hormone , fetus , biology , genetics
Summary Levels of adrenocorticotrophic hormone (ACTH) and cortisol were measured in amniotic fluid during labour and in maternal blood during and after labour. There was a significant rise of maternal ACTH and cortisol levels during labour and a significant decrease after delivery in all 14 patients studied. There were no significant changes in amniotic fluid ACTH and cortisol levels during labour. The initial level of ACTH in amniotic fluid (162·7 pg/ml) was higher than that in maternal circulation (120·2 pg/ml). The correlation between maternal and amniotic fluid ACTH was not significant while the corresponding correlation for cortisol values was.