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A LONGITUDINAL STUDY OF THE FREE CORTISOL INDEX IN PREGNANCY
Author(s) -
Brien T. G.,
Dalrymple I. J.
Publication year - 1976
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1976.tb00843.x
Subject(s) - index (typography) , pregnancy , longitudinal study , obstetrics , medicine , mathematics , statistics , computer science , biology , world wide web , genetics
Summary Total plasma cortisol, the ‘cortisol resin uptake ratio’ (cortisol RUR), and ‘free cortisol index’ (FCI) were estimated in 23 pregnant women from 12 weeks to term and at six weeks post partum . Total plasma cortisol rose continually throughout pregnancy; the cortisol RUR rose up to 20 to 23 weeks and then fell slowly and the FCI also rose although more slowly than the total cortisol. All parameters fell to non‐pregnant levels at six weeks post partum . It is confirmed that a true rise in metabolically active cortisol occurs during pregnancy.