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PLASMA OESTRIOL AND HUMAN PLACENTAL LACTOGEN MEASUREMENTS IN PATIENTS WITH HIGH RISK PREGNANCIES
Author(s) -
Edwards R. P.,
Diver M. J.,
Davis J. C.,
Hipkin L. J.
Publication year - 1976
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1976.tb00815.x
Subject(s) - human placental lactogen , placental lactogen , fetal distress , asphyxia , medicine , fetal growth , obstetrics , fetus , endocrinology , pregnancy , plasma concentration , incidence (geometry) , placenta , biology , genetics , physics , optics
Summary Maternal plasma oestriol and human placental lactogen (HPL) were measured serially in 383 at‐risk pregnancies. Eighty‐five infants were growth retarded and 122 developed fetal distress or neonatal asphyxia. Of the infants whose mothers had either abnormal plasma oestriol or HPL levels, 58 per cent were growth retarded, while 65 and 73 per cent in each group respectively developed fetal distress. The incidence of fetal complications when both plasma oestriol and HPL were abnormal was consistently greater than 66 per cent.