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RELATIONSHIP OF ORAL CONTRACEPTION TO DEVELOPMENT OF TROPHOBLASTIC TUMOUR AFTER EVACUATION OF A HYDATIDIFORM MOLE
Author(s) -
Stone M.,
Dent J.,
Kardana A.,
Bagshawe K. D.
Publication year - 1976
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1976.tb00774.x
Subject(s) - gynecology , medicine , oral contraception , mole , trophoblastic tumor , obstetrics , choriocarcinoma , excretion , family planning , pregnancy , population , research methodology , gestation , biology , environmental health , genetics
Summary The need for chemotherapy for trophoblastic tumour after evacuation of a hydatidiform mole was found to be significantly increased in patients taking oral contraceptives before normal human chorionic gonadotrophin (HCG) values were obtained. Oral contraception was also found to delay the fall in HCG excretion in patients not requiring treatment with cytotoxic drugs.