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THE EFFECT OF PROLACTIN ON THE RESPONSE OF HUMAN LYMPHOCYTES TO PHYTOHAEMAGGLUTININ
Author(s) -
Karmali R. A.,
Horrobin D. F.
Publication year - 1976
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1976.tb00771.x
Subject(s) - phytohaemagglutinin , prolactin , endocrinology , medicine , pregnancy , lymphocyte , biology , chemistry , hormone , genetics
Summary Lymphocytes were collected from ten normal human males and incubated with or without phytohaemagglutinin (PHA) in the absence or presence of ovine prolactin in concentrations found in normal individuals and in human pregnancy. Prolactin consistently inhibited lymphocyte transformations. The degree of inhibition became progressively less as PHA concentrations were increased.