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THE EFFECTS OF THE FENOTEROL HY DROBROMIDE (PARTUSISTEN) AEROSOL ON UTERINE ACTIVITY AND THE CARDIOVASCULAR SYSTEM
Author(s) -
Lipshitz J.,
Baillie P.
Publication year - 1976
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1976.tb00762.x
Subject(s) - fenoterol , oxytocin , placebo , aerosol , crossover study , medicine , vasopressin , anesthesia , chemistry , asthma , alternative medicine , organic chemistry , pathology
Summary Fenoterol hydrobromide (Partusisten) aerosol was used in a placebo‐controlled, double‐blind, double crossover trial to study its effects on oxytocin‐induced uterine contractions and the maternal cardiovascular system. The active and placebo aerosols were each administered a total of ten times or twice each in five patients who were in established oxytocin‐induced labour with intact membranes. Five puffs, of 200 μg each, of the active aerosol reduced uterine activity by more than half; the effect on the cardiovascular system was to cause a mild tachycardia and to widen the pulse pressure.