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NEONATAL HYPERBILIRUBINAEMIA FOLLOWING THE USE OF PROSTAGLANDIN E 2 IN LABOUR
Author(s) -
Beazley J. M.,
Weekes A. R. L.
Publication year - 1976
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1976.tb00732.x
Subject(s) - prostaglandin e2 , prostaglandin , economics , medicine , labour economics , endocrinology
Summary A prospective study of 447 labours and the resulting newborn failed to reveal any significant difference between the incidence of neonatal hyperbilirubinaemia, denned as a level of at least 205 μmol/1 (12 mg/100 ml), following spontaneous labour and after labour induced or accelerated with prostaglandin E 2 (PGE 2 ). The incidence of unexplained neonatal hyperbilirubinaemia after spontaneous labour was 4 ± 5 per cent. There was no significant association betweeen the incidence of neonatal hyperbilirubinaemia and the total dose of PGE 2 used for induction. None of the babies of the six mothers who required more than 1.5 mg of PGE 2 to induce labour developed hyperbilirubinaemia. No association was demonstrated between neonatal hyperbilirubinaemia and birth weight or the duration of labour. The implications of these findings are discussed.