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MORPHOLOGICAL CHANGES IN MATERNAL LYMPHOCYTES IN PREGNANCY
Author(s) -
Knobloch Viktor,
Jouja Vladimir,
Svobodová Marie
Publication year - 1975
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1975.tb02213.x
Subject(s) - nucleolus , pregnancy , staining , incidence (geometry) , lymphocyte , andrology , third trimester , medicine , physiology , obstetrics , biology , fetus , pathology , immunology , genetics , physics , nucleus , psychiatry , optics
Summary By use of staining with toluidine blue, the changes in the nucleoli of lymphocytes in 150 healthy women were studied. The patients were divided into five groups: non‐pregnant women; women in the first, second and third trimesters of pregnancy; and women who were five days post parturn. A progressive and statistically significant rise in the number of lymphocytes with micronucleoli was found during pregnancy and there was a fall after delivery. This increase was associated with a decrease in the incidence of ring‐shaped nucleoli. There were no significant changes in the absolute number of lymphocytes and in “active” lymphocytes during pregnancy.