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ASSESSMENT OF THYROID FUNCTION DURING PREGNANCY
Author(s) -
Chan Vivian,
Paraskevaides C. A.,
Hale J. F.
Publication year - 1975
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1975.tb02211.x
Subject(s) - euthyroid , triiodothyronine , pregnancy , medicine , endocrinology , thyroid function , thyroid , hormone , thyroid stimulating hormone , thyroid function tests , gestation , biology , genetics
Summary Serum levels of thyroid stimulating hormone and of the two thyroid hormones were compared in pregnant women and in non‐pregnant control subjects. Circulating levels of thyroid stimulating hormone did not alter significantly throughout pregnancy. Total thyroxine and triiodothyronine concentrations increased markedly during the first and second trimesters, associated with a progressive increase in the thyroid binding capacity of serum proteins. Urinary triiodothyronine and thyroxine excretion during the third trimester of pregnancy was comparable to that found in non‐pregnant euthyroid females and, it is concluded, provides the simplest method of assessing thyroid function during pregnancy.