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COMPARISON OF INTRAVENOUS OXYTOCIN AND PROSTAGLANDIN E 2 FOR INDUCTION OF LABOUR USING AUTOMATIC AND NON‐AUTOMATIC INFUSION TECHNIQUES
Author(s) -
Calder A. A.,
Embrey M. P.
Publication year - 1975
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1975.tb00713.x
Subject(s) - oxytocin , prostaglandin e2 , medicine , cervix , labor induction , anesthesia , prostaglandin , prostaglandin e , induction of labor , obstetrics , pregnancy , biology , cancer , genetics
Summary A double blind trial of prostaglandin E 2 and oxytocin given by intravenous infusion after amniotomy for induction of labour in 100 primigravidae with unfavourable induction features is reported. No clear‐cut advantage of either drug emerged although PGE 2 was perhaps superior when the cervix was highly unfavourable. Prostaglandin E 2 appeared to produce less deleterious effects on the fetus but was associated with a higher incidence of maternal side effects. The automatic Cardiff Infusion apparatus was found to be a safe means of PGE 2 infusion and to have advantages over the use of non‐automatic techniques both for PGE 2 and for oxytocin infusion.