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THE EFFECTS ON PLATELET AGGREGATION OF ORAL PROSTAGLANDIN E 2 USED FOR THE INDUCTION OF LABOUR
Author(s) -
Myatt L.,
Elder M. G.
Publication year - 1975
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1975.tb00668.x
Subject(s) - prostaglandin e2 , platelet aggregation , medicine , platelet , oral administration , prostaglandin , venous blood
Summary Secondary ADP induced platelet aggregation was inhibited in 17 patients after the administration of oral prostaglandin E 2 tablets for the induction of labour. Primary ADP induced aggregation was shown to be inhibited by oral prostaglandin E 2 when the platelets responded to the lower concentration of 0.5 μg/ml of ADP.This inhibition was not detectable when the higher concentration of 1 0 μg/ml ADP was necessary. There would appear to be a decreased risk of thrombosis initiated by platelet aggregation as a result of using oral PGE 2 tablets for inducing labour.