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THE PROGNOSTIC VALUE OF HUMAN PLACENTAL LACTOGEN (HPL) LEVELS IN THREATENED ABORTION
Author(s) -
Gartside M. W.,
Tindall V. R.
Publication year - 1975
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1975.tb00639.x
Subject(s) - threatened abortion , gestation , human placental lactogen , placental lactogen , abortion , medicine , obstetrics , threatened species , pregnancy , biology , fetus , placenta , genetics , ecology , habitat
Summary The value of a single HPL, estimation in serum was assessed in 337 patients with a threatened abortion between 7 and 27 weeks gestation. Serial assays were subsequently performed on 75 of these. A scheme is proposed whereby an HPL result can be given a “favourable”, “equivocal” or “unfavourable” prognosis according to its level. Using this scheme a correct prognosis was obtained in 86 per cent of cases between 9 and 19 weeks gestation while an incorrect prognosis was obtained in 3 per cent of cases. There appeared to be little prognostic value after 19 weeks gestation though prior to 9 weeks the results were sufficiently promising to suggest that a more sensitive assay would be useful.