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AN EVALUATION OF HUMAN PLACENTAL LACTOGEN LEVELS IN HYPERTENSION OF PREGNANCY
Author(s) -
Kelly Anne M.,
England P.,
Lorimer J. D.,
Ferguson J. C.,
Govan A. D. T.
Publication year - 1975
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1975.tb00633.x
Subject(s) - human placental lactogen , asphyxia , placental lactogen , fetal distress , medicine , fetus , endocrinology , pregnancy , obstetrics , placenta , biology , genetics
Summary Maternal plasma levels of human placental lactogen (HPL) are decreased in hypertensive pregnancies and the concentration is related to the severity of the condition. Of infants who had HPL concentrations in the fetal danger zone (more than 2 SD's below normal mean) 75 per cent developed fetal distress, neonatal asphyxia or were light for dates. Patients who are identified in this way have lighter infants and placentae than their unidentified counterparts with normal HPL levels.