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PLASMA PROGESTERONE AND OESTRADIOL‐17β CHANGES DURING ABORTION INDUCED BY PROSTAGLANDIN F 2α
Author(s) -
Tyack A. J.,
Lambadarios Carol,
Parsons R. J.,
Stewart C. R.,
Cooke I. D.
Publication year - 1974
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1974.tb00364.x
Subject(s) - prostaglandin f2alpha , radioimmunoassay , prostaglandin , endocrinology , medicine , abortion , endocrine system , plasma concentration , pregnancy , chemistry , hormone , biology , genetics
Summary Plasma levels of progesterone and oestradiol‐17β were measured using radio‐immunoassay methods in 52 blood samples obtained from 10 women aborting after intra‐amniotic instillation of prostaglandin F 2α . Mean falls in plasma progesterone of 55.7 per cent and in oestradiol‐17β of 46.6 per cent were noted. There was a highly significant correlation between falling concentrations of both steroids and the instillation‐abortion interval (p<0.001).