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THE INDUCTION OF OVULATION BY TAMOXIFEN
Author(s) -
Williamson J. G.,
Ellis J. D.
Publication year - 1973
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1973.tb11230.x
Subject(s) - tamoxifen , medicine , ovulation induction , infertility , gynecology , ovulation , anovulation , abortion , menstrual cycle , obstetrics , clinical trial , pregnancy , cancer , hormone , biology , breast cancer , insulin resistance , polycystic ovary , insulin , genetics
Summary A new anti‐oestrogen, tamoxifen, has been synthesized and is available for clinical trials. Its value in the treatment of anovulatory infertility has been assessed in 32 patients. A total of 26 patients apparently ovulated, 16 patients conceived during a treatment cycle, and 2 patients became pregnant during the first spontaneous cycle thereafter. There was no increase in the abortion rate and there were no multiple pregnancies. Side‐effects were uncommon and none were serious.

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