Premium
PLASMA VOLUME AND GLOMERULAR FILTRATION RATE IN PREGNANCY AND THEIR RELATION TO DIFFERENCES IN FETAL GROWTH
Author(s) -
Gibson Helen M.
Publication year - 1973
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1973.tb02981.x
Subject(s) - renal function , pregnancy , obstetrics , medicine , plasma volume , endocrinology , biology , genetics
Summary Plasma volume and glomerular filtration rate were measured serially during pregnancy and again three months after delivery in nine healthy multigravidae with normal past obstetric histories, and in eleven multigravidae who had a history of reproductive failure (“poor reproducers”). The increase of plasma volume was less in the “poor reproducers” than in the normal women, largely but not entirely associated with babies of lower birthweight. As a reflection of the association there was a marked negative correlation between the birthweight of the baby and the lowest haemoglobin concentration reached by the mother. The rise in glomerular filtration rate was also less in the “poor reproducers” than in the normal women and in pregnancies where the baby was small the rate tended to fall from its peak value during the second half of pregnancy.