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A COMPARISON OF ORAL PROSTAGLANDIN E 2 AND INTRAVENOUS SYNTOCINON IN THE INDUCTION OF LABOUR
Author(s) -
Kelly John,
Flynn Anna M.,
Bertrand Philip V.
Publication year - 1973
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1973.tb02153.x
Subject(s) - medicine , vomiting , incidence (geometry) , prostaglandin e2 , apgar score , anesthesia , nausea , obstetrics , pregnancy , gestational age , biology , genetics , physics , optics
Summary Prostaglandin E 2 (PGE 2 ) was administered by mouth to induce labour in 49 patients. A similar number of matched controls were induced by Syntocinon intravenously. PGE 2 was successful in 47 patients and Syntocinon in 46. There was no significant difference between the two groups for the induction to delivery interval, for the Apgar scores of the babies at one and five minutes, or for the incidence of postpartum haemorrhage. The resting uterine tone, frequency of uterine contractions and incidence of inco‐ordinate uterine activity were, however, all significantly greater in the Syntocinon group. Vomiting and diarrhoea appeared to be more common in the patients induced with PGE 2 but no statistical comparison was possible because these side effects were only specifically recorded in the patients in the PGE 2 series. The greater incidences of pyrexia and acetonuria in the Syntocinon group were not statistically significant.