Premium
SERUM SEROMUCOID AND THE MATERNO‐PATERNAL MIXED LEUCOCYTE REACTION FOLLOWING PREVIOUS SEVERE PRE‐ECLAMPSIA
Author(s) -
Jenkins D. M.,
Good W.,
Good Sheila M.
Publication year - 1973
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1973.tb02123.x
Subject(s) - eclampsia , etiology , medicine , immune system , immunology , preeclampsia , pregnancy , obstetrics , biology , genetics
Summary A group of 12 parous women was investigated following severe pre‐eclampsia or eclampsia to see if there was any relationship between serum seromucoid levels, known to be elevated in some of these patients, and cell mediated immune reactions in mixed cultures of their leucocytes and those of their husbands. Statistically significant linear correlations were demonstrated. High levels of maternal serum seromucoid are apparently immunosuppressive in materno‐paternal mixed leucocyte reactions. The possible significance of these findings in relation to the aetiology of pre‐eclampsia or eclampsia is discussed.