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THE USE OF DIAZEPAM AND HYDRALLAZINE IN THE TREATMENT OF SEVERE PRE‐ECLAMPSIA
Author(s) -
Joyce D. N.,
Kenyon V. G.
Publication year - 1972
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1972.tb15792.x
Subject(s) - eclampsia , diazepam , anesthesia , medicine , lytic cycle , blood pressure , pregnancy , virus , genetics , virology , biology
Summary An intravenous infusion of diazapan and hydrallazine was given to 52 patients with severe pre‐eclampsia in labour. The results of this treatment have been compared with those from a similar group of patients treated with a lytic cocktail regime or rectal Avertin (tribromethanol). Diazepam and hydrallazine gave significantly better control of blood pressure than the lytic and Avertin regimes without producing any adverse reactions other than a tendency to hypothermia in the newborn. No patient developed eclampsia while being treated with diazepan and hydrallazine, but one patient had a fit while being treated with a lytic cocktail and had a further fit after subsequent Avertin treatment.