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ENDOCRINE FUNCTION IN RHESUS ISO‐IMMUNIZATION
Author(s) -
Fairweather D. V. I.,
Billewicz W.,
Loraine J. A.,
Bell E. T.
Publication year - 1972
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1972.tb15761.x
Subject(s) - gestation , endocrine system , pregnanediol , medicine , hormone , urine , physiology , immunization , pregnancy , obstetrics , endocrinology , immunology , antigen , biology , genetics
Summary Serial assays of oestrone, oestriol, pregnanediol and chorionic gonadotrophin have been made in maternal urine from 32 weeks gestation until delivery in rhesus immunized patients whose infants suffered from haemolytic disease o varying severity. The results were compared with those from a series of normally pregnant women of comparable age and gestation period. In the rhesus patients no correlation could be demonstrated between severity of disease and endocrine profile. Assays of hormones and their metabolites were of little or no value in the management of patients with rhesus immunization.