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RADIUM MENOPAUSE: A LONG‐TERM FOLLOW‐UP
Author(s) -
Bamford D. S.,
Wagman H.
Publication year - 1972
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1972.tb15756.x
Subject(s) - medicine , menopause , radium , malignancy , sex organ , gynecology , physics , biology , nuclear physics , genetics
Summary Ninety‐three patients have been traced out of 110 who were treated by induction of a radium meniopause in 1950 and 1951. The method was very successful: were no seruous postoperative complications and patients suffered neither recurrence of dysfunctional bleedign nor distressing menopausal symptoms. However seven women subsequently developed malignant tumours and six of these involved the genital ract. The fact that two of these were pelvic sarcomas may support the view that pelvic irradiation promotes the development of sarcoma. This, together with the knowledge that women with abnormal bleeding in the 5th and 6th decades already have an increased risk of uterine malignancy, supports the view that redium menopause should be considered only in the treatment of women who are poor surgical risks.