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THE BRENNER TUMOUR OF THE OVARY
Author(s) -
Fox H.,
Agrawal K.,
Langley F. A.
Publication year - 1972
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1972.tb14220.x
Subject(s) - serous fluid , medicine , pathology , ovary , calcification , pathological , endometrial hyperplasia , hyperplasia
Summary The clinical and pathological features of 54 cases of Brenner tumour of the ovary have been reviewed. One tumour was considered to be malignant and one to be of the “proliferative” type; the remainder showed the characteristic features of Brenner tumours and many were of microscopic size only. Cystic change, mucinous metaplasia, stromal calcification, stronial hyalinosis and thecosis were common histological features. Thirteen of the tumours were in combination with mucinous or serous tumours or with a benign cystic teratoma. Three were bilateral. A very high proportion of the tumours were asymptomatic and were incidental findings during the investigation or treatment of some other condition. Abdominal symptoms or abnormal vaginal bleeding occur as symptoms of a small proportion of cases of Brenner tumour and there is an association of this tumour with cystic hyperplasia of the endometrium; the degree of endometrial hyperplasia is usually mild and rarely produces symptoms. A small proportion of Brenner tumours are presumed to be oestrogenic but it has not proved possible to correlate any morphological features of the tumour with presumed hormonal activity.