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STATISTICAL ANALYSTS OF RELATIONSHIP BETWEEN ORAL CONTRACEPTIVES, SECONDARY AMENORRHOEA AND GALACTORRHOEA
Author(s) -
Shearman Rodney P.,
Smith Ian D.
Publication year - 1972
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1972.tb14218.x
Subject(s) - medicine , amenorrhea , gynecology , family planning , galactorrhea , research methodology , obstetrics , population , pregnancy , hormone , genetics , environmental health , prolactin , biology
Summary The association of secondary amenorrhoea with galactorrhoea and a history of oral contraceptive treatment in a series of 230 patients has been analyzed. Ninety‐six (4·17 per cent) developed their syndrome after treatment with oral contraceptives. Comparing these observations with the known usage of oral contraceptives in Australia, there is a highly significant (P<0.0l) relationship between the use of oral contraceptives and the subsequent development of amenorrhoea. Somewhat surprisingly, although amenorrhoea‐galactorrhoea is more commonly associated with a history of oral contraceptives than any other factor, such history had no effect upon the proportion of secondary amenorrhoea patients with concurrent galactorrhoea.