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THE ORIGIN OF HEAT‐STABLE PLACENTAL ALKALINE PHOSPHATASE
Author(s) -
Watkins Wayne B.,
Anderson Sheridah R. A.
Publication year - 1971
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1971.tb01630.x
Subject(s) - trophoblast , alkaline phosphatase , placental alkaline phosphatase , placenta , enzyme , endocrinology , chemistry , medicine , andrology , biology , pregnancy , biochemistry , fetus , genetics
Summary The relative volume of trophoblast and the heat‐stable alkaline phosphatase activity were determined in normal and pre‐eclamptic placentae. The enzyme levels were lower in the pre‐eclamptic than in the normal placentae and there was a significant correlation between these levels and the proportion of the trophoblastic tissue. It is concluded that human placental heat‐stable alkaline phosphatase originates from the trophoblast.