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THYROID‐STIMULATING HORMONE IN SERUM OF MOTHER AND NEWBORN AT BIRTH
Author(s) -
Dokumov Stoyan I.,
Milanov Stefan Ch.,
Trepetshov Stefan P.
Publication year - 1971
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1971.tb00343.x
Subject(s) - medicine , hormone , endocrinology , thyroid , thyroid stimulating hormone , fetus , stimulation , thyroid function , pregnancy , biology , genetics
Summary Serum thyroid‐stimulating hormone (TSH) was assayed by the radio‐biological method of Querido et al. (1953) in 50 pairs of mothers and newborn infants. As a control 20 healthy, non‐pregnant women were examined. Compared to that of normal, non‐pregnant women the maternal serum TSH concentration was raised. The serum TSH level of the newborn immediately after delivery was about half that of healthy, non‐pregnant women and much reduced in comparison with that of the mother in labour. From these results it was concluded that maternal TSH does not pass through the placental barrier. The development and function of the fetal thyroid depend on TSH stimulation from the fetal pituitary and are unrelated to maternal pituitary stimulation.