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PREGNANCY RESULTS FOLLOWING TREATMENT WITH CLOMIPHENE CITRATE
Author(s) -
Murray Moira,
OsmondClarke F.
Publication year - 1971
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1971.tb00233.x
Subject(s) - cervical mucus , pregnancy , ovulation , infertility , pregnancy rate , medicine , gynecology , clomifene , menotropins , obstetrics , physiology , ovulation induction , endocrinology , biology , hormone , genetics
Summary Three hundred and twenty‐eight infertile women were selected for treatment with clomiphene citrate because the sole cause of their infertility was absent or infrequent ovulation; this was induced in 66.4 per cent with an overall pregnancy rate of 52 per cent. Six types of cytological response to clomiphene are described together with the effect on cervical mucus. Improved results were obtained by a more careful selection of patients and with greater use of combined therapy with human chorionic gonadotrophin, when the ovulatory response rose to 74 per cent with pregnancy rate of 63 per cent.