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SCANNING ELECTRON MICROSCOPY IN THE STUDY OF CERVICAL NEOPLASIA
Author(s) -
Jordan J.A.,
Williams A. E.
Publication year - 1971
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1971.tb00209.x
Subject(s) - epithelium , in situ , carcinoma in situ , pathology , electron microscope , scanning electron microscope , basal cell , biology , morphology (biology) , squamous carcinoma , ultrastructure , carcinoma , anatomy , chemistry , optics , medicine , zoology , physics , organic chemistry
Summary Scanning electron microscopy has been used to study normal and abnormal cervical epithelia. Normal columnar epithelium and normal squamous epithelium have been identified and described. Carcinoma in situ has also been examined and characteristic differences in tissue organization and cell morphology have been recognized. The surfaces of normal squamous cells are arranged with interconnecting microridges, whereas the surface epithelium from carcinoma in situ cells is arranged in closly packed microvilli. The significance of these results and the possible potential of the technique in studying the natural history of carcinoma in situ are discussed.