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A COMPARATIVE STUDY OF BLOOD FIBRINOLYTIC ACTIVITY IN NORMAL WOMEN, PREGNANT WOMEN AND WOMEN ON ORAL CONTRACEPTIVES
Author(s) -
Me I. Sudhakaran,
Peberdy Mary,
Rannie G. H.,
Weightman Doris,
Dewar H. A.
Publication year - 1970
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1970.tb03604.x
Subject(s) - chlormadinone acetate , medicine , endocrinology , gynecology , population , research methodology , environmental health
Summary A decrease in blood fibrinolytic activity in women taking chlormadinone compared with normal women was found (p<0.01). The mean fibrinolytic activity in pregnant women was significantly lower than that of normal women, those taking chlormadinone acetate and also those on a combined oestrogen‐progestagen preparation (p<0.001). No significant difference in fibrinolytic inhibitor content was observed when normal women were compared with pregnant women (p>0.2) and those taking chlormadinone (p>0.3). On the other hand, the women on a combined oestrogen‐progestagen preparation had a lower fibrinolytic inhibitor content than both normal women (p<0.001) and those receiving chlormadinone (p<0.02).