Premium
THE ACTION OF PROSTAGLANDINS ON THE HUMAN ISOLATED NON‐PREGNANT CERVIX
Author(s) -
Najak Zeeba,
Hillier Keith,
Karim S. M. M.
Publication year - 1970
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1970.tb03595.x
Subject(s) - isometric exercise , cervix , oxytocin , contraction (grammar) , medicine , muscle contraction , endocrinology , motility , prostaglandins f , peristalsis , constriction , isotonic , prostaglandin , anatomy , biology , cancer , genetics
Summary The isolated non‐pregnant cervix has been shown to exhibit spontaneous isotonic and isometric contractility and to respond to drugs. PGE 2 causes a marked relaxation whilst the effect of PGF 2α is more variable. Oxytocin and adrenaline cause contraction of the muscle. The implications of the finding that the cervix can show isotonic and isometric contractility and the effects of prostaglandins are discussed.