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TREATMENT OF PRIMARY AMENORRHOEA WITH HUMAN PITUITARY AND CHORIONIC GONADOTROPHINS
Author(s) -
Gemzell C.,
Carlborg L.,
Johansson E. D. B.,
Roos P.
Publication year - 1970
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1970.tb03408.x
Subject(s) - pregnancy , medicine , abortion , amenorrhea , gynecology , obstetrics , menotropins , pregnanediol , endocrinology , hormone , ovulation , biology , ovulation induction , genetics
Summary Fifteen infertile women with primary amenorrhoea and pronounced oestrogen deficiency were treated with human pituitary gonadotrophin and human chorionic gonadotrophin 71 times; 61 ovulations (86 per cent) were recorded. Eleven patients conceived (73·5 per cent), three of them twice and one three times, giving 16 pregnancies in all. There were 12 single births and four sets of twins. Two pregnancies ended in abortion. On average one pregnancy resulted from 4·5 treatments and clinical symptoms of overstimulation occurred in 2 cycles (2·8 per cent).