I. Three Cases of Epithelioma of the Vulva with the After‐Histories. *

P.J., a married woman, aet. 47, was admitted into the London Hospital on the 5th December, 1896. She had been married 24 years and had had five children-the last 11 years previously-also 3 miscarriages-the last 8 years previously. . The catamenia had been regular every 4 weeks until the beginning of 1896. From January to March “nothing was seen,” and she had thought herself pregnant. Two normal periods, howeyer, followed in April and May. Since that time there had been amenorrhoea up to the time of her admission. Her father died at 72 of apoplexy; her mother is still alive, Eet. 51. She was born in Bristol, and lived there till she married in 1873. She had lived all her married life in the East of London. At about the age of 18, she suffered from marked debility, and about that time also is said to have had typhus fever. After the birth of the second child in 1877 she had an attack of eccema affecting the soles and the palms, which lasted six months; and another attack of it, lasting about four months during her third pregnancy in 1879. She appeared also to have suffered from attacks during the 7 years prior to her admission. She then had a swelling equal in size to a hen’s egg underneath the left knee, and at the same time she had a bad bilious attack. She was treated for this, and the swelling disappeared. During the same months some small warts made their appearance-5 on the back of the left hand, 5 on the right cheek, and 3 on the right labium majus. Those on the hand and cheek were scraped away by the patient herself with the finger nail, and the scars left from this looked like small burns. CASE I.