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An evaluation of P50 paired‐click methodologies
Author(s) -
Dalecki Anna,
Croft Rodney J.,
Johnstone Stuart J.
Publication year - 2011
Publication title -
psychophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.661
H-Index - 156
eISSN - 1469-8986
pISSN - 0048-5772
DOI - 10.1111/j.1469-8986.2011.01262.x
Subject(s) - psychology , cognitive psychology
The utility of P50 paired‐click measures is limited by their unestablished reliability, unknown effects of time, and long protocol. This study measured within‐session reliability, temporal course, effect of varying interpair interval (IPI), and peak definition and ratio calculation methods on P50 paired‐click measures in healthy participants. Results indicate higher reliability for difference (ICC=.72) than ratio (ICC=.44) method; when P50 peaks are defined as baseline‐to‐peak than peak‐to‐peak; time‐related changes; and comparable P50 paired‐click measures at long (9 s) and short (3–7 s) IPIs. After controlling for time effects, P50 paired‐click measures are relatively reliable within‐session and are best measured using the difference method and defined as baseline‐to‐peak amplitude; time effects must be taken into account when measuring P50 paired‐click measures in a long paradigm; and IPI can be shortened in studies with healthy samples.