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Nonlinear relationship between electrodermal activity and heart rate variability in patients with acute schizophrenia
Author(s) -
Rachow Tobias,
Berger Sandy,
Boettger Michael Karl,
Schulz Steffen,
Guinjoan Salvador,
Yeragani Vikram K.,
Voss Andreas,
Bär KarlJürgen
Publication year - 2011
Publication title -
psychophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.661
H-Index - 156
eISSN - 1469-8986
pISSN - 0048-5772
DOI - 10.1111/j.1469-8986.2011.01210.x
Subject(s) - heart rate variability , psychology , heart rate , skin conductance , medicine , cardiology , autonomic nervous system , schizophrenia (object oriented programming) , tonic (physiology) , psychosis , audiology , blood pressure , psychiatry , neuroscience , biomedical engineering
We investigated to what degree tonic skin conductance levels (SCL) and cardiac autonomic dysfunction are interrelated in schizophrenia. Heart rate variability (HRV) and SCL were simultaneously assessed in 18 unmedicated patients and 18 controls matched for age, sex, weight, and smoking habits. For comparison to prior studies, phasic sympathetic skin responses (SPR) were also recorded. Compared to controls, patients had prolonged SPR latency and reduced SPR amplitude with a right‐greater‐than‐left asymmetry, which was inversely correlated with positive symptoms. An autonomic imbalance was reflected in linear and nonlinear measures of HRV and increased SCL. Patients showed a stronger nonlinear association between SCL and heart rate than controls. HRV and SCL findings were strongly affected by group differences in breathing rate. Stronger HRV‐SCL coupling in patients may suggest augmented sympathetic modulation in schizophrenia.