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Association between Cold Face Test‐induced vagal inhibition and cortisol response to acute stress
Author(s) -
Marca Roberto La,
Waldvogel Patricia,
Thörn Hanna,
Tripod Mélanie,
Wirtz Petra H.,
Pruessner Jens C.,
Ehlert Ulrike
Publication year - 2011
Publication title -
psychophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.661
H-Index - 156
eISSN - 1469-8986
pISSN - 0048-5772
DOI - 10.1111/j.1469-8986.2010.01078.x
Subject(s) - vagal tone , psychology , mood , trier social stress test , heart rate , medicine , analysis of variance , vagus nerve , endocrinology , stressor , stimulation , heart rate variability , fight or flight response , clinical psychology , blood pressure , neuroscience , biochemistry , chemistry , gene
Low vagal function is related to several disorders. One possible underlying mechanism linking the vagus nerve and disorders is the HPA axis. Thirty‐three healthy male subjects participated in a stress task, while heart rate (HR), respiratory sinus arrhythmia (RSA), salivary cortisol, and mood were assessed. Vagal function was determined using baseline, stress‐induced inhibition, and Cold Face Test (CFT)‐induced stimulation. The stress task induced a significant increase in cortisol and HR, a decrease in RSA, and a worsening of mood. A linear regression model with the time from CFT onset until maximum bradycardia as the independent variable explained 17.9% of the total variance in cortisol in response to the stressor (mood: 36.5%). The results indicate that a faster CFT response is associated with reduced cortisol increase and enhanced mood after acute stress. Our data support an inverse relationship between vagal function and the HPA axis.